产品货号：
Z12775
中文名称：
C6orf173/CENPW抗体
英文名称：
Anti-C6orf173/CENPW Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-C6orf173/CENPW Antibody |
| 指标别名 | C6orf173,CENP W,CENPW,Centromere protein W,CUG2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB |
| 基因名称 | CENPW |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | CENPW antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human CENPW.The immunogen is located within the first 50 amino acids of CENPW. |
| 计算分子量 | 10kDa |
| 成分 | CENPW Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | CENPW Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | CENPW was initially identified as a gene that was upregulated in multiple cancers,and whose overexpression in mouse fibroblast cells gave rise to distinct cancer-specific phenotypes.It was later found to be a nuclear protein that associated with CENPT,a component of CENPA nucleosome complex in the centromere,and is required for proper kinetochore function.CENPW also specifically interacts with the nucleolar phosphoprotein nucleophosmin,also known as B23 It has been suggested that nucleophosmin functions in the assembly of the kinetochore by interacting with CENPW during interphase.Overexpression of CENPW in the SKOV-3 human ovarian cancer cell line as well as in the zebrafish embryo led to apoptosis,suggesting that high levels of CENPW induces apoptotic cell death. |
| Uniprot ID | Q5EE01 |
| 基因名全称 | Centromere protein W |
| 蛋白名全称 | Centromere protein W |
| 推荐稀释比 | CENPW antibody can be used for detection of CENPW by Western blot at 0.5 ～ 1μg/mL.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
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